{"id":42829,"date":"2023-11-20T02:53:39","date_gmt":"2023-11-20T08:53:39","guid":{"rendered":"https:\/\/stage.cancerimagingarchive.net\/collection\/mouse-astrocytoma\/"},"modified":"2023-11-20T02:53:39","modified_gmt":"2023-11-20T08:53:39","slug":"mouse-astrocytoma","status":"publish","type":"tcia_collection","link":"https:\/\/stage.cancerimagingarchive.net\/collection\/mouse-astrocytoma\/","title":{"rendered":"MOUSE-ASTROCYTOMA"},"featured_media":0,"template":"","class_list":["post-42829","tcia_collection","type-tcia_collection","status-publish"],"cancer_types":["Glioblastoma Multiforme"],"citations":[42825,9225],"collection_doi":"10.7937\/K9TCIA.2017.SGW7CAQW","collection_download_info":"","collection_downloads":[42827],"versions":false,"additional_resources":"<p>The NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.<\/p>\n<li><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=mouse_astrocytoma\">Imaging Data Commons (IDC)<\/a> (Imaging Data)<\/li>","cancer_locations":["Head"],"collection_page_accessibility":"Public","publications_related":"","version_change_log_archived":"<h3>Version 1 (Current): Updated 2017\/03\/21<\/h3>\n<table><colgroup> <col\/> <col\/> <\/colgroup><tbody><tr><th colspan=\"1\">Data Type<\/th><th colspan=\"1\">Download all or Query\/Filter<\/th><\/tr><tr><td colspan=\"1\">Images ( 2.0 GB)<\/td><td colspan=\"1\"><div><p>\n<a download=\"Mouse-Astrocytoma-doiJNLP.tcia\" href=\"\/wp-content\/uploads\/Mouse-Astrocytoma-doiJNLP.tcia\"><button><i><\/i> Download<\/button><\/a>\u00a0\n\n<a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=Mouse-Astrocytoma\"><button><i><\/i> Search<\/button><\/a>\u00a0\n\u00a0\u00a0<a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=Mouse-Astrocytoma\">\u00a0<\/a><\/p><p>(Download requires\u00a0the\u00a0<a href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><\/tr><\/tbody><\/table>","collection_status":"Complete","publications_using":"<p>TCIA maintains\u00a0<a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\">a list of publications<\/a>\u00a0which leverage our data.\u00a0If you have a manuscript you'd like to add, please <a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\">contact TCIA's Helpdesk<\/a>.<\/p>","related_analysis_results":false,"species":["Mouse"],"version_number":"1","collection_title":"Mouse-Astrocytoma","date_updated":"2017-03-21","related_collection":false,"subjects":"48","analysis_results":"","collection_short_title":"Mouse-Astrocytoma","data_types":["MR"],"version_change_log":"","collection_browse_title":"Mouse-Astrocytoma","detailed_description":"<p>A presentation about this data set can be found at:\u00a0<strong> <a data-linked-resource-container-id=\"24283583\" data-linked-resource-container-version=\"24\" data-linked-resource-content-type=\"application\/vnd.ms-powerpoint\" data-linked-resource-default-alias=\"Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\" data-linked-resource-id=\"24642133\" data-linked-resource-type=\"attachment\" data-linked-resource-version=\"1\" data-nice-type=\"PowerPoint Presentation\" download=\"Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\" href=\"\/wp-content\/uploads\/Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\">Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt<\/a> <\/strong>.<\/p>","supporting_data":false,"collection_featured_image":false,"collection_summary":"<p>This collection consists of magnetic resonance images (MRI) of genetically engineered mouse models (GEMMs) of high grade astrocytoma, including glioblastoma multiforme (GBM).<\/p>\n<p>In these GEMMs, the most commonly disregulated networks in GBM -- RB, KRAS and\/or PI3K signaling -- are perturbed at the genetic level.\u00a0 These genetic aberrations induce development of high grade astrocytoma in the mouse with properties similar to that of human disease.\u00a0 MRI was used to perform a qualitative and quantitative phenotypic characterization of the different genotypes and molecular subtypes.\u00a0 Additionally, mouse MRI images were compared human GBM imaging parameters using the VASARI lexicon.\u00a0 The MRI data contained herein includes anatomic T2 weighted images and dynamic contrast enhanced MRI.<\/p>\n<p>For scientific or other inquiries about this dataset, please <a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\">contact TCIA's Helpdesk<\/a>.<\/p>","collection_acknowledgements":"<p><strong>  \u00a0  <\/strong>We would like to acknowledge the individuals and institutions that have provided data for this collection:<\/p>\n<ul><li><strong>  \u00a0  <\/strong> <strong>National Cancer Institute (Frederick, Maryland) -\u00a0<\/strong>Special thanks to<strong>\u00a0Sunny Jansen, PhD<\/strong>\u00a0 from the Department of\u00a0  <strong>Mouse Cancer Genetics Program.<\/strong> <\/li><\/ul>","collection_funding":"","hide_from_browse_table":"0","program":["Community"],"_links":{"self":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections\/42829","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections"}],"about":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/wp\/v2\/types\/tcia_collection"}],"version-history":[{"count":0,"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections\/42829\/revisions"}],"wp:attachment":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/wp\/v2\/media?parent=42829"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}