{"id":42835,"date":"2023-11-20T02:54:09","date_gmt":"2023-11-20T08:54:09","guid":{"rendered":"https:\/\/stage.cancerimagingarchive.net\/collection\/mouse-mammary\/"},"modified":"2023-11-20T02:54:09","modified_gmt":"2023-11-20T08:54:09","slug":"mouse-mammary","status":"publish","type":"tcia_collection","link":"https:\/\/stage.cancerimagingarchive.net\/collection\/mouse-mammary\/","title":{"rendered":"MOUSE-MAMMARY"},"featured_media":0,"template":"","class_list":["post-42835","tcia_collection","type-tcia_collection","status-publish"],"cancer_types":["Breast Cancer"],"citations":[42831,9225],"collection_doi":"10.7937\/K9\/TCIA.2015.9P42KSE6","collection_download_info":"","collection_downloads":[42833],"versions":false,"additional_resources":"<p>The NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.<\/p>\n<li><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=mouse_mammary\">Imaging Data Commons (IDC)<\/a> (Imaging Data)<\/li>","cancer_locations":["Abdomen"],"collection_page_accessibility":"Public","publications_related":"","version_change_log_archived":"<h3>Version 1 (Current): Updated 2015\/03\/18<\/h3>\n<table><colgroup><col\/><col\/><\/colgroup><tbody><tr><th colspan=\"1\">Data Type<\/th><th colspan=\"1\">Download all or Query\/Filter<\/th><\/tr><tr><td colspan=\"1\">Images (8.6GB)<\/td><td colspan=\"1\"><div><p>\n<a download=\"TCIA_Mouse-Mammary_06-22-2015.tcia\" href=\"\/wp-content\/uploads\/TCIA_Mouse-Mammary_06-22-2015.tcia\"><button><i><\/i> Download<\/button><\/a>\u00a0\n\n<a href=\"https:\/\/www.cancerimagingarchive.net\/nbia-search\/?CollectionCriteria=Mouse-mammary\"><button><i><\/i> Search<\/button><\/a>\u00a0\n<br\/><\/p><p>(Download requires\u00a0the\u00a0<a href=\"https:\/\/wiki.cancerimagingarchive.net\/display\/NBIA\/Downloading+TCIA+Images\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><\/tr><\/tbody><\/table>","collection_status":"Complete","publications_using":"<p>TCIA maintains <a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\">a list of publications<\/a> which leverage TCIA data.  If you have a manuscript you'd like to add please<a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\"> contact TCIA's Helpdesk<\/a>.<\/p>","related_analysis_results":false,"species":["Mouse"],"version_number":"1","collection_title":"Mouse-Mammary","date_updated":"2015-03-18","related_collection":false,"subjects":"32","analysis_results":"","collection_short_title":"Mouse-Mammary","data_types":["MR"],"version_change_log":"","collection_browse_title":"Mouse-Mammary","detailed_description":"<p>A presentation about a related Mouse GBM data set can be found at:\u00a0<strong><a data-linked-resource-container-id=\"20644280\" data-linked-resource-container-version=\"75\" data-linked-resource-content-type=\"application\/vnd.ms-powerpoint\" data-linked-resource-default-alias=\"Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\" data-linked-resource-id=\"20807725\" data-linked-resource-type=\"attachment\" data-linked-resource-version=\"1\" data-nice-type=\"PowerPoint Presentation\" download=\"Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\" href=\"\/wp-content\/uploads\/Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt\">Sunny_jansen_NBIA_mouseGBM_update_ICR_508.ppt<\/a><\/strong>.<\/p>","supporting_data":false,"collection_featured_image":false,"collection_summary":"This collection consists of magnetic resonance images (MRI) of genetically engineered mouse models (GEMMs) of breast cancer.\u00a0 These images were acquired as part of a Department of Defense (DOD) Breast Cancer Research Program (BCRP) Postdoctoral Award W81XWH-12-1-0307 entitled \u201c<em>Investigating Ductal Carcinoma in Situ Using Noninvasive Imaging of Genetically Engineered Mouse Models<\/em>\n<p>A particular emphasis of this project was to study the earliest stages of breast cancer\u2014preinvasive ductal carcinoma <em>in situ <\/em>(DCIS)\u2014and to interrogate the underlying genetic events that influence progression into invasive disease. In particular, we focused on the role of perturbed Rb, p53 and BRCA1 functionality and how these pathways, acting alone and in combination, can influence the development and progression of DCIS. GEMMs serve as an excellent model system wherein genetic changes can be controlled and manipulated over time.\u00a0 <em>In vivo<\/em> MRI is a superb technique for noninvasively tracking and characterizing these microscopic early stage cancers as they develop, change and transition into lethal invasive disease.<\/p>\n<p>For scientific or other inquiries about this dataset, please <a href=\"https:\/\/www.cancerimagingarchive.net\/support\/\">contact TCIA's Helpdesk<\/a>.<\/p>","collection_acknowledgements":"<p><strong>\u00a0<\/strong>We would like to acknowledge the individuals and institutions that have provided data for this collection:<\/p>\n<ul><li><strong>\u00a0<\/strong><strong>National Cancer Institute (Frederick, Maryland) -\u00a0<\/strong>Special thanks to<strong>\u00a0Sunny Jansen, PhD<\/strong>\u00a0 from the Department of\u00a0<strong>Mouse Cancer Genetics Program.<\/strong><\/li><\/ul>\n<p><strong><br\/><\/strong><\/p>","collection_funding":"","hide_from_browse_table":"0","program":["Community"],"_links":{"self":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections\/42835","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections"}],"about":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/wp\/v2\/types\/tcia_collection"}],"version-history":[{"count":0,"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections\/42835\/revisions"}],"wp:attachment":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/wp\/v2\/media?parent=42835"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}