{"id":43039,"date":"2023-11-20T03:06:17","date_gmt":"2023-11-20T09:06:17","guid":{"rendered":"https:\/\/stage.cancerimagingarchive.net\/collection\/nsclc-radiomics-interobserver1\/"},"modified":"2024-09-19T09:17:40","modified_gmt":"2024-09-19T14:17:40","slug":"nsclc-radiomics-interobserver1","status":"publish","type":"tcia_collection","link":"https:\/\/stage.cancerimagingarchive.net\/collection\/nsclc-radiomics-interobserver1\/","title":{"rendered":"NSCLC-RADIOMICS-INTEROBSERVER1"},"featured_media":7119,"template":"","class_list":["post-43039","tcia_collection","type-tcia_collection","status-publish","has-post-thumbnail"],"cancer_types":["Non-small Cell Lung Cancer"],"citations":[43017,43019,43021,9225],"collection_doi":"10.7937\/tcia.2019.cwvlpd26","collection_download_info":"","collection_downloads":[43023,43025],"versions":[43035,43037],"additional_resources":"The NCI Cancer Research Data Commons (CRDC) provides access to additional data and a cloud-based data science infrastructure that connects data sets with analytics tools to allow users to share, integrate, analyze, and visualize cancer research data.\r\n<ul>\r\n \t<li><a href=\"https:\/\/portal.imaging.datacommons.cancer.gov\/explore\/filters\/?collection_id=nsclc_radiomics_interobserver1\">Imaging Data Commons (IDC)<\/a>\u00a0(Imaging Data)<\/li>\r\n<\/ul>","cancer_locations":["Lung"],"collection_page_accessibility":"Public","publications_related":"<span style=\"color: #ffffff;\">\u00a0.\u00a0<\/span>","version_change_log_archived":"<h3>Version 3 (Current): Updated 2020\/08\/31<\/h3><table><colgroup><col \/><col \/><\/colgroup><tbody><tr><th>Data Type<\/th><th>Download all or Query\/Filter<\/th><\/tr><tr><td>Images (DICOM, 3.2 GB)<\/td><td><div><p><a href=\"\/wp-content\/uploads\/NSCLC-RADIOMICS-INTEROBSERVER1-Aug-31-2020-NBIA-manifest.tcia\" download=\"NSCLC-RADIOMICS-INTEROBSERVER1-Aug-31-2020-NBIA-manifest.tcia\"><button><i><\/i> Download<\/button><\/a>\u00a0 <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=NSCLC-RADIOMICS-INTEROBSERVER1\"><button><i><\/i> Search<\/button><\/a>\u00a0 <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=NSCLC-RADIOMICS-INTEROBSERVER1\">\u00a0<\/a><\/p><p>(Download requires\u00a0the\u00a0<a href=\"\/display\/NBIA\/Downloading+TCIA+Images\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\">Clinical Data (CSV)<\/td><td colspan=\"1\"><div><p><a href=\"\/wp-content\/uploads\/Interobserver1.clinical_updated_released_2019-June-17.csv\" download=\"Interobserver1.clinical_updated_released_2019-June-17.csv\"><button><i><\/i> Download<\/button><\/a>\u00a0<\/p><\/div><\/td><\/tr><\/tbody><\/table><p>Resolved the inadvertent mismatch of the labels between the DICOM Segmentations and the RTSTRUCT annotations. Version 2 was replaced.<\/p><h3>Version 2: Updated 2019\/10\/18<\/h3><table><colgroup><col \/><col \/><\/colgroup><tbody><tr><th>Data Type<\/th><th>Download all or Query\/Filter<\/th><\/tr><tr><td>Images (DICOM, 3.2 GB)<\/td><td><div><p><a href=\"\/wp-content\/uploads\/NSCLC-RADIOMICS-INTEROBSERVER1-Oct2019-NBIA-manifest.tcia\" download=\"NSCLC-RADIOMICS-INTEROBSERVER1-Oct2019-NBIA-manifest.tcia\"><button><i><\/i> Download<\/button><\/a>\u00a0 <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=NSCLC-RADIOMICS-INTEROBSERVER1\"><button><i><\/i> Search<\/button><\/a>\u00a0 <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=NSCLC-RADIOMICS-INTEROBSERVER1\">\u00a0<\/a><\/p><p>(Download requires\u00a0the\u00a0<a href=\"\/display\/NBIA\/Downloading+TCIA+Images\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\">Clinical Data (CSV)<\/td><td colspan=\"1\"><div><p><a href=\"\/wp-content\/uploads\/Interobserver1.clinical_updated_released_2019-June-17.csv\" download=\"Interobserver1.clinical_updated_released_2019-June-17.csv\"><button><i><\/i> Download<\/button><\/a>\u00a0<\/p><\/div><\/td><\/tr><\/tbody><\/table><p>Added DICOM Segmentations for the primary tumor only, the ROI (GTV-1) for the RTSTRUCTs and DICOM Segs are the same.<\/p><h3>Version 1: Updated 2019\/06\/02<\/h3><table><colgroup><col \/><col \/><\/colgroup><tbody><tr><th>Data Type<\/th><th>Download all or Query\/Filter<\/th><\/tr><tr><td>Images (DICOM, 2.0 GB)<\/td><td><div><p><a href=\"\/wp-content\/uploads\/NSCLC-RADIOMICS-INTEROBSERVER1-NBIA-manifest.tcia\" download=\"NSCLC-RADIOMICS-INTEROBSERVER1-NBIA-manifest.tcia\"><button><i><\/i> Download<\/button><\/a>\u00a0 <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=NSCLC-RADIOMICS-INTEROBSERVER1\"><button><i><\/i> Search<\/button><\/a>\u00a0 <a href=\"https:\/\/nbia.cancerimagingarchive.net\/nbia-search\/?MinNumberOfStudiesCriteria=1&amp;CollectionCriteria=NSCLC-RADIOMICS-INTEROBSERVER1\">\u00a0<\/a><\/p><p>(Download requires\u00a0the\u00a0<a href=\"\/display\/NBIA\/Downloading+TCIA+Images\">NBIA Data Retriever<\/a>)<\/p><\/div><\/td><\/tr><tr><td colspan=\"1\">Clinical Data (CSV)<\/td><td colspan=\"1\"><div><p><a href=\"\/wp-content\/uploads\/Interobserver1.clinical_updated_released_2019-June-17.csv\" download=\"Interobserver1.clinical_updated_released_2019-June-17.csv\"><button><i><\/i> Download<\/button><\/a>\u00a0<\/p><\/div><\/td><\/tr><\/tbody><\/table>","collection_status":"Complete","publications_using":"TCIA maintains<a href=\"https:\/\/www.cancerimagingarchive.net\/publications\/\"> a list of publications<\/a> which leverage our data. If you have a manuscript you'd like to add please <a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\">contact TCIA's Helpdesk<\/a>.","related_analysis_results":[45529],"species":["Human"],"version_number":"3","collection_title":"NSCLC-Radiomics-Interobserver1","date_updated":"2020-08-31","related_collection":false,"subjects":"22","analysis_results":"","collection_short_title":"NSCLC-Radiomics-Interobserver1","data_types":["CT","RTSTRUCT","SEG"],"version_change_log":"<span style=\"color: #212121;\">Resolved the inadvertent mismatch of the labels between the DICOM Segmentations and the RTSTRUCT annotations. Version 2 was replaced.<\/span>","collection_browse_title":"NSCLC-Radiomics-Interobserver1","detailed_description":"","supporting_data":["Clinical"],"collection_featured_image":{"ID":"7119","post_author":"29","post_date":"2023-09-13 09:32:26","post_date_gmt":"2023-09-13 14:32:26","post_content":"","post_title":"NSCLC-RADIOMICS-GRAPHIC","post_excerpt":"","post_status":"inherit","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nsclc-radiomics-graphic","to_ping":"","pinged":"","post_modified":"2023-12-04 12:50:07","post_modified_gmt":"2023-12-04 18:50:07","post_content_filtered":"","post_parent":"42417","guid":"https:\/\/stage.cancerimagingarchive.net\/wp-content\/uploads\/NSCLC-RADIOMICS-GRAPHIC.jpg","menu_order":"0","post_type":"attachment","post_mime_type":"image\/jpeg","comment_count":"0","pod_item_id":"7119"},"collection_summary":"<p>This collection contains clinical data and computed tomography (CT) from 22 non-small cell lung cancer (NSCLC) radiotherapy patients. For 21 of these patients with pre-treatment CT scans, repeated blinded manual delineations by five different radiation oncologists of the 3D volume of the gross tumor volume on CT and clinical outcome data are available. The above was repeated with the same set of five radiation oncologists, using an in-house autosegmentation tool for initial delineation followed by manual adjustment of the primary gross tumor volume outline. For one patient, clinical data and CT was available but the tumor delineations were not extracted. This patient was included in this collection for the sake of completeness.<\/p><p>This dataset refers to the \"Multiple delineation\" dataset of the study published in Nature Communications (<a href=\"https:\/\/doi.org\/10.1038\/ncomms5006\">https:\/\/doi.org\/10.1038\/ncomms5006<\/a>). In short, the publication used a radiomics approach to computed tomography data of 1,019 patients with lung or head-and-neck cancer. Radiomics refers to the comprehensive quantification of tumor phenotypes by applying a large number of quantitative image features. In the published analysis, 440 features quantifying tumor image intensity, shape, and texture were extracted. We found that a large number of radiomic features have prognostic power in independent data sets, many of which were not identified as significant before. Radiogenomics analysis revealed that a prognostic radiomic signature, capturing intra-tumor heterogeneity, was associated with underlying gene-expression patterns. These data suggest that radiomics identifies a general prognostic phenotype existing in both lung and head-and-neck cancer. This may have a clinical impact as imaging is routinely used in clinical practice, providing an unprecedented opportunity to improve decision-support in cancer treatment at low cost.<\/p><p>The delineations are provided in two formats; DICOM RTSTRUCT contains slice by slice contour points of the external outline of the primary tumour. DICOM SEGMENTATION contains binary masks of the same primary tumour. The nomenclature of the structures are as follows:<\/p><ul><li>\u201cGTV-1\u201d denotes the index tumour, specifically the Gross Tumour Volume (GTV)<\/li><li>\u201cvis\u201d denotes manual delineation by radiation oncologists<\/li><li>\u201cauto\u201d denotes assistance by an\u00a0autosegmentation\u00a0tool followed with manual editing by radiation oncologists<\/li><li>\u201c1\u201d, \u201c2\u201d, \u2026., \u201c5\u201d denotes the individual radiation oncologists working independently of each other<\/li><\/ul><p>Side note : Radiation oncologists denoted \u201c1\u201d and \u201c3\u201d were trainee radiation oncologists at the time of this experiment. Radiation oncologists \u201c2\u201d, \u201c4\u201d and \u201c5\u201d were extensively experienced at the time of this experiment.<\/p><p>This dataset is intended to be open access to support repeatability and reproducibility of research in the radiomics domain. This dataset has been referenced in Medical Physics Dataset Article addressing FAIR radiomics practices to support transparency, harmonization and collaboration on radiomics (<a href=\"https:\/\/doi.org\/10.1002\/mp.14322\">https:\/\/doi.org\/10.1002\/mp.14322<\/a>).<\/p><p>&nbsp;<\/p><p>Other data sets in the Cancer Imaging Archive that were used in the same\u00a0<a href=\"http:\/\/www.nature.com\/ncomms\/2014\/140603\/ncomms5006\/full\/ncomms5006.html\">study published in Nature Communications<\/a>:\u00a0<a href=\"\/collection\/head-neck-radiomics-hn1\/\" target=\"_blank\" rel=\"noopener\">HEAD-NECK-RADIOMICS-HN1<\/a>,\u00a0<a href=\"\/collection\/nsclc-radiomics-interobserver1\/\" target=\"_blank\" rel=\"noopener\">NSCLC-Radiomics-Interobserver1<\/a>,\u00a0<a href=\"\/collection\/nsclc-radiomics-genomics\/\" target=\"_blank\" rel=\"noopener\">NSCLC-Radiomics-Genomics<\/a>, <a href=\"\/analysis-result\/rider-lungct-seg\/\" target=\"_blank\" rel=\"noopener\">RIDER-LungCT-Seg<\/a>.<\/p><p>For scientific or other inquiries about this dataset, please\u00a0<a href=\"http:\/\/www.cancerimagingarchive.net\/support\/\">contact TCIA's Helpdesk<\/a>.<\/p>","collection_acknowledgements":"<p>We would like to acknowledge the individuals and institutions that have provided data for this collection:<\/p><ul><li>Leonard Wee, MAASTRO (Dept of Radiotherapy), Maastricht University Medical Centre+, Maastricht, Limburg, The Netherlands.<\/li><li>Dirk de\u00a0Ruysscher, MAASTRO (Dept of Radiotherapy), Maastricht University Medical Centre+, Maastricht, Limburg, The Netherlands.<\/li><li>Andre Dekker, MAASTRO (Dept of Radiotherapy), Maastricht University Medical Centre+, Maastricht, Limburg, The Netherlands.<\/li><li>Hugo\u00a0Aerts, Computational Imaging and Bioinformatic Laboratory, Dana-Farber Cancer Institute &amp; Harvard Medical School, Boston, Massachusetts, USA.<\/li><li>Petros Kalendralis, MAASTRO (Dept of Radiotherapy), Maastricht University Medical Centre+, Maastricht, Limburg, The Netherlands.<\/li><li>Harmonization of the components of this dataset, including into\u00a0standard DICOM representation, was supported in part by the NCI\u00a0Imaging Data Commons consortium. NCI Imaging Data Commons consortium\u00a0is supported by the contract number 19X037Q from Leidos Biomedical\u00a0Research under Task Order HHSN26100071 from NCI.<\/li><\/ul>","collection_funding":"","hide_from_browse_table":"0","program":["Community"],"_links":{"self":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections\/43039","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections"}],"about":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/wp\/v2\/types\/tcia_collection"}],"version-history":[{"count":1,"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections\/43039\/revisions"}],"predecessor-version":[{"id":47887,"href":"https:\/\/stage.cancerimagingarchive.net\/api\/v1\/collections\/43039\/revisions\/47887"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stage.cancerimagingarchive.net\/api\/wp\/v2\/media\/7119"}],"wp:attachment":[{"href":"https:\/\/stage.cancerimagingarchive.net\/api\/wp\/v2\/media?parent=43039"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}