REMBRANDT | REMBRANDT

DOI: 10.7937/K9/TCIA.2015.588OZUZB | Data Citation Required | Image Collection

Summary

Finding better therapies for the treatment of brain tumors is hampered by the lack of consistently obtained molecular data in a large sample set and the ability to integrate biomedical data from disparate sources enabling translation of therapies from bench to bedside. Hence, a critical factor in the advancement of biomedical research and clinical translation is the ease with which data can be integrated, redistributed, and analyzed both within and across functional domains. Novel biomedical informatics infrastructure and tools are essential for developing individualized patient treatment based on the specific genomic signatures in each patient's tumor. The Repository of Molecular Brain Neoplasia Data (REMBRANDT) is aimed at facilitating discovery by connecting the dots between clinical information and genomic characterization data.

REMBRANDT contains data generated through the Glioma Molecular Diagnostic Initiative from 874 glioma specimens comprising approximately 566 gene expression arrays, 834 copy number arrays, and 13,472 clinical phenotype data points. These data are currently housed in Georgetown University's G-DOC System and are described in a related manuscript .  This image collection was created as a companion data set to augment the larger REMBRANDT project. It contains the pre-surgical magnetic resonance (MR) multi-sequence images from 130 REMBRANDT patients. 

Data Access

Some data in this collection contains images that could potentially be used to reconstruct a human face. To safeguard the privacy of participants, users must sign and submit a TCIA Restricted License Agreement to help@cancerimagingarchive.net before accessing the data.

Version 2: Updated 2021/08/17

Some rows in the Clinical Data file were found to be misaligned per column headers:

row 39,87,93,104: right shift by one (change within MRI findings or OnStudy Therapy Chemo Agent Name)
row 46,57: right shift by 2 (change within MRI Findings)

these realign CSV with no further adjustments made to content.

Additional Resources for this Dataset

The following external resources are also available.  These are not hosted or supported by TCIA, but may be useful to researchers utilizing this collection.

• Molecular/Clinical Data in G-DOC
• Segmentation Labels for the REMBRANDT brain cancer MRI image collection are available on NITRC and are described in this Nature Scientific Data publication

Citations & Data Usage Policy

Data Citation Required: Users must abide by the TCIA Data Usage Policy and Restrictions. Attribution must include the following citation, including the Digital Object Identifier: